🧬 基因注释：SERPINE1
📝 官方信息
官方名称：serpin family E member 1
功能摘要：This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. [provided by RefSeq, Aug 2020].
🎯 作为靶基因的剪接因子
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- QKI 综合评分: 0.412 · 证据 1 条
- RBFOX2 综合评分: 0.398 · 证据 2 条
- HNRNPL 综合评分: 0.362 · 证据 2 条
- HNRNPC 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- PCBP2 综合评分: 0.344 · 证据 1 条
- TIA1 综合评分: 0.312 · 证据 1 条
- PRPF8 综合评分: 0.262 · 证据 1 条
- MSI1 综合评分: 0.212 · 证据 1 条
- Srsf1 综合评分: 0.212 · 证据 1 条
- Mbnl2 综合评分: 0.200 · 证据 1 条
- PCBP1 综合评分: 0.200 · 证据 2 条
- SF3A3 综合评分: 0.200 · 证据 1 条
- AQR 综合评分: 0.150 · 证据 1 条
- PRPF4 综合评分: 0.150 · 证据 1 条
- TFIP11 综合评分: 0.150 · 证据 1 条
- Tardbp 综合评分: 0.150 · 证据 1 条
- U2af1 综合评分: 0.150 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录