🧬 基因注释：SERPINE1
📝 官方信息
官方名称：serpin family E member 1
功能摘要：This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. [provided by RefSeq, Aug 2020].
🎯 作为靶基因的剪接因子
- CSTF2T 置信度: 2.0
- HNRNPA2B1 置信度: 2.0
- HNRNPC 置信度: 2.0
- HNRNPL 置信度: 2.0
- HNRNPM 置信度: 2.0
- MBNL1 置信度: 2.0
- PCBP1 置信度: 2.0
- RBFOX2 置信度: 2.0
- AQR 置信度: 1.0
- MSI1 置信度: 1.0
- Mbnl2 置信度: 1.0
- PCBP2 置信度: 1.0
- PRPF4 置信度: 1.0
- PRPF8 置信度: 1.0
- QKI 置信度: 1.0
- Rbm7 置信度: 1.0
- Rnps1 置信度: 1.0
- SAFB 置信度: 1.0
- SF3A3 置信度: 1.0
- Sf3b1 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录