🧬 基因注释:SIGLEC1
📝 官方信息
官方名称:sialic acid binding Ig like lectin 1
功能摘要:This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. The protein plays an important role in multiple human diseases and bacterial and viral infections has been shown to enhance SARS-CoV-2 infection. [provided by RefSeq, Dec 2021].
🎯 作为靶基因的剪接因子
- RBM39 置信度: 2.0
🏥 关联疾病
该基因暂无关联疾病记录