🧬 基因注释：SIGMAR1
📝 官方信息
官方名称：sigma receptor chaperone 1
功能摘要：This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2013].
🎯 作为靶基因的剪接因子
- HNRNPL 综合评分: 0.514 · 证据 2 条
- HNRNPC 综合评分: 0.510 · 证据 2 条
- Tardbp 综合评分: 0.468 · 证据 1 条
- HNRNPK 综合评分: 0.424 · 证据 2 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- FUS 综合评分: 0.398 · 证据 1 条
- Srsf3 综合评分: 0.398 · 证据 1 条
- fus 综合评分: 0.398 · 证据 1 条
- PCBP2 综合评分: 0.360 · 证据 1 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- QKI 综合评分: 0.350 · 证据 1 条
- Rnps1 综合评分: 0.314 · 证据 1 条
- UPF1 综合评分: 0.306 · 证据 1 条
- HNRNPU 综合评分: 0.300 · 证据 2 条
- PTBP1 综合评分: 0.300 · 证据 2 条
- RBFOX2 综合评分: 0.300 · 证据 2 条
- SRSF3 综合评分: 0.300 · 证据 1 条
- SRSF9 综合评分: 0.300 · 证据 1 条
- Mbnl2 综合评分: 0.262 · 证据 1 条
- PRPF8 综合评分: 0.262 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录