SpliceAtlasDB
← 返回上一页

🧬 基因注释:SNW1

📝 官方信息

官方名称:SNW domain containing 1

功能摘要:This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].

🎯 作为靶基因的剪接因子
🏥 关联疾病
cancer
(0.579)
dengue disease
(0.370)
neurodegenerative disease
(0.261)
🔍 查看该基因的所有关联疾病
🔗 外部数据库链接