🧬 基因注释：SOD2
📝 官方信息
官方名称：superoxide dismutase 2
功能摘要：This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016].
🎯 作为靶基因的剪接因子
- HNRNPH1 综合评分: 0.474 · 证据 2 条
- FUS 综合评分: 0.460 · 证据 1 条
- fus 综合评分: 0.460 · 证据 1 条
- HNRNPM 综合评分: 0.448 · 证据 2 条
- HNRNPK 综合评分: 0.362 · 证据 2 条
- PTBP1 综合评分: 0.362 · 证据 2 条
- Nova2 综合评分: 0.360 · 证据 1 条
- HNRNPA2B1 综合评分: 0.350 · 证据 2 条
- HNRNPC 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- ELAVL3 综合评分: 0.348 · 证据 1 条
- Tardbp 综合评分: 0.336 · 证据 1 条
- MBNL2 综合评分: 0.324 · 证据 1 条
- UPF1 综合评分: 0.306 · 证据 1 条
- HNRNPD 综合评分: 0.300 · 证据 2 条
- HNRNPL 综合评分: 0.300 · 证据 2 条
- HNRNPU 综合评分: 0.300 · 证据 2 条
- KHSRP 综合评分: 0.300 · 证据 2 条
- RBFOX2 综合评分: 0.300 · 证据 2 条
- SRSF3 综合评分: 0.300 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录