🧬 基因注释：SPARC
📝 官方信息
官方名称：secreted protein acidic and cysteine rich
功能摘要：This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2015].
🎯 作为靶基因的剪接因子
- CPSF4 置信度: 2.0
- CSTF2T 置信度: 2.0
- HNRNPA1 置信度: 2.0
- HNRNPL 置信度: 2.0
- NOVA1 置信度: 2.0
- PTBP1 置信度: 2.0
- RBFOX2 置信度: 2.0
- RBM20 置信度: 2.0
- ELAVL3 置信度: 1.0
- FUS 置信度: 1.0
- MBNL2 置信度: 1.0
- MSI1 置信度: 1.0
- Mbnl2 置信度: 1.0
- Nova2 置信度: 1.0
- PCBP2 置信度: 1.0
- PRPF8 置信度: 1.0
- Ptbp2 置信度: 1.0
- QKI 置信度: 1.0
- Rbpms 置信度: 1.0
- Srsf1 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录