🧬 基因注释：SRSF10
📝 官方信息
官方名称：serine and arginine rich splicing factor 10
功能摘要：This gene product is a member of the serine-arginine (SR) family of proteins, which are involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein interacts with the oncoprotein TLS, and abrogates the influence of TLS on adenovirus E1A pre-mRNA splicing. This gene has pseudogenes on chromosomes 4, 9, 14, 18, and 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].
🎯 作为靶基因的剪接因子
- HNRNPC 综合评分: 0.510 · 证据 2 条
- FUS 综合评分: 0.474 · 证据 1 条
- fus 综合评分: 0.474 · 证据 1 条
- HNRNPA1 综合评分: 0.412 · 证据 2 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- HNRNPM 综合评分: 0.412 · 证据 2 条
- HNRNPK 综合评分: 0.398 · 证据 2 条
- HNRNPL 综合评分: 0.362 · 证据 2 条
- KHSRP 综合评分: 0.362 · 证据 2 条
- PTBP1 综合评分: 0.362 · 证据 2 条
- Srsf2 综合评分: 0.362 · 证据 1 条
- Srsf3 综合评分: 0.362 · 证据 1 条
- HNRNPH1 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- EWSR1 综合评分: 0.348 · 证据 2 条
- ELAVL3 综合评分: 0.329 · 证据 1 条
- PCBP2 综合评分: 0.324 · 证据 1 条
- PRPF8 综合评分: 0.324 · 证据 1 条
- FUBP1 综合评分: 0.312 · 证据 2 条
- RBM22 综合评分: 0.312 · 证据 2 条
🏥 关联疾病
neurodegenerative disease
中关联 (0.541)
prostate carcinoma
低关联 (0.319)
Abnormality of the skeletal system
低关联 (0.194)
smoking initiation
低关联 (0.192)
hepatocellular carcinoma
低关联 (0.104)