🧬 基因注释：SRSF5
📝 官方信息
官方名称：serine and arginine rich splicing factor 5
功能摘要：The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016].
🎯 作为靶基因的剪接因子
- HNRNPM 综合评分: 0.474 · 证据 2 条
- HNRNPA1 综合评分: 0.412 · 证据 2 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- HNRNPC 综合评分: 0.412 · 证据 2 条
- HNRNPF 综合评分: 0.412 · 证据 2 条
- HNRNPH1 综合评分: 0.412 · 证据 2 条
- FUBP1 综合评分: 0.410 · 证据 2 条
- HNRNPU 综合评分: 0.398 · 证据 2 条
- CELF2 综合评分: 0.372 · 证据 2 条
- FUS 综合评分: 0.362 · 证据 1 条
- KHSRP 综合评分: 0.362 · 证据 2 条
- RBFOX2 综合评分: 0.362 · 证据 2 条
- Srsf2 综合评分: 0.362 · 证据 1 条
- fus 综合评分: 0.362 · 证据 1 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- QKI 综合评分: 0.350 · 证据 1 条
- Ptbp2 综合评分: 0.344 · 证据 1 条
- NOVA1 综合评分: 0.324 · 证据 2 条
- PRPF8 综合评分: 0.324 · 证据 1 条
- Rnps1 综合评分: 0.314 · 证据 1 条
🏥 关联疾病
Abnormality of the skeletal system
中关联 (0.465)
neurodegenerative disease
低关联 (0.371)
dengue disease
低关联 (0.370)
bone remodeling disease
低关联 (0.270)
neuroendocrine neoplasm
低关联 (0.237)