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🧬 基因注释:SSTR1

📝 官方信息

官方名称:somatostatin receptor 1

功能摘要:Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28. [provided by RefSeq, Jul 2012].

🎯 作为靶基因的剪接因子
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • SRSF3 综合评分: 0.300 · 证据 1 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • MBNL2 综合评分: 0.200 · 证据 1 条
  • ELAVL3 综合评分: 0.162 · 证据 1 条
  • CSTF2 综合评分: 0.150 · 证据 2 条
  • TFIP11 综合评分: 0.150 · 证据 1 条
  • EIF4A3 综合评分: 0.100 · 证据 2 条
  • Srsf7 综合评分: 0.100 · 证据 1 条
  • UPF1 综合评分: 0.100 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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