SpliceAtlasDB
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🧬 基因注释:STAU1

📝 官方信息

官方名称:staufen double-stranded RNA binding protein 1

功能摘要:Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. [provided by RefSeq, Apr 2020].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.510 · 证据 2 条
  • FUS 综合评分: 0.506 · 证据 1 条
  • fus 综合评分: 0.506 · 证据 1 条
  • Tardbp 综合评分: 0.444 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • HNRNPM 综合评分: 0.412 · 证据 2 条
  • HNRNPK 综合评分: 0.362 · 证据 2 条
  • HNRNPA1 综合评分: 0.350 · 证据 2 条
  • HNRNPH1 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • QKI 综合评分: 0.350 · 证据 1 条
  • CELF2 综合评分: 0.324 · 证据 2 条
  • PCBP1 综合评分: 0.324 · 证据 2 条
  • RBM15 综合评分: 0.312 · 证据 2 条
  • UPF1 综合评分: 0.306 · 证据 1 条
  • HNRNPD 综合评分: 0.300 · 证据 2 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
🏥 关联疾病
response to corticosteroid
低关联 (0.296)
poisoning
低关联 (0.294)
response to salmeterol
低关联 (0.293)
hypertension
低关联 (0.282)
intelligence
低关联 (0.272)
major depressive disorder
低关联 (0.229)
insomnia
低关联 (0.158)
aging
低关联 (0.113)
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🔗 外部数据库链接