🧬 基因注释：STING1
📝 官方信息
官方名称：stimulator of interferon response cGAMP interactor 1
功能摘要：This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014].
🎯 作为靶基因的剪接因子
- CELF2 置信度: 2.0
- CPSF4 置信度: 2.0
- CSTF2T 置信度: 2.0
- EIF4A3 置信度: 2.0
- HNRNPA2B1 置信度: 2.0
- HNRNPC 置信度: 2.0
- HNRNPK 置信度: 2.0
- HNRNPM 置信度: 2.0
- MBNL1 置信度: 2.0
- PTBP1 置信度: 2.0
- AQR 置信度: 1.0
- PRPF8 置信度: 1.0
- Rbpms 置信度: 1.0
- Rnps1 置信度: 1.0
- Srsf1 置信度: 1.0
- Tardbp 置信度: 1.0
- U2af1 置信度: 1.0
- U2af2 置信度: 1.0
- UPF1 置信度: 1.0
- YBX1 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录