🧬 基因注释：SFPQ
📝 官方信息
官方名称：splicing factor proline and glutamine rich
功能摘要：Enables DNA binding activity; histone deacetylase binding activity; and protein homodimerization activity. Involved in several processes, including alternative mRNA splicing, via spliceosome; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; and regulation of transcription by RNA polymerase II. Acts upstream of or within double-strand break repair via homologous recombination. Located in chromatin; nuclear matrix; and paraspeckles. [provided by Alliance of Genome Resources, Apr 2022]
🎯 作为靶基因的剪接因子
- HNRNPC 综合评分: 0.524 · 证据 2 条
- Srsf3 综合评分: 0.460 · 证据 1 条
- HNRNPA1 综合评分: 0.412 · 证据 2 条
- HNRNPD 综合评分: 0.398 · 证据 2 条
- HNRNPK 综合评分: 0.362 · 证据 2 条
- HNRNPU 综合评分: 0.362 · 证据 2 条
- PTBP1 综合评分: 0.362 · 证据 2 条
- SRSF3 综合评分: 0.362 · 证据 1 条
- HNRNPA2B1 综合评分: 0.350 · 证据 2 条
- HNRNPF 综合评分: 0.350 · 证据 2 条
- HNRNPH1 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- U2af2 综合评分: 0.348 · 证据 1 条
- U2af1 综合评分: 0.336 · 证据 1 条
- RBM10 综合评分: 0.312 · 证据 2 条
- RBM22 综合评分: 0.312 · 证据 2 条
- TIA1 综合评分: 0.312 · 证据 1 条
- FUS 综合评分: 0.300 · 证据 1 条
- HNRNPL 综合评分: 0.300 · 证据 2 条
🏥 关联疾病
tuberculosis
低关联 (0.370)
Endometrial Endometrioid Adenocarcinoma
低关联 (0.370)
hepatocellular carcinoma
低关联 (0.298)
melanoma
低关联 (0.296)
non-small cell lung carcinoma
低关联 (0.283)
lung adenocarcinoma
低关联 (0.281)
allergic rhinitis
低关联 (0.280)
papillary renal cell carcinoma
低关联 (0.280)
esophageal adenocarcinoma
低关联 (0.279)
bladder transitional cell carcinoma
低关联 (0.279)