🧬 基因注释：SNAP25

官方名称：synaptosome associated protein 25

功能摘要：Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

• HNRNPC 综合评分: 0.412 · 证据 2 条
• Ptbp2 综合评分: 0.406 · 证据 1 条
• HNRNPK 综合评分: 0.362 · 证据 2 条
• FUS 综合评分: 0.300 · 证据 1 条
• PTBP1 综合评分: 0.300 · 证据 2 条
• fus 综合评分: 0.300 · 证据 1 条
• Tardbp 综合评分: 0.274 · 证据 1 条
• Mbnl2 综合评分: 0.262 · 证据 1 条
• Rnps1 综合评分: 0.244 · 证据 1 条
• CELF2 综合评分: 0.212 · 证据 2 条
• MBNL2 综合评分: 0.200 · 证据 1 条
• Nova2 综合评分: 0.200 · 证据 1 条
• CSTF2 综合评分: 0.150 · 证据 2 条
• MSI1 综合评分: 0.150 · 证据 1 条
• Srsf1 综合评分: 0.150 · 证据 1 条
• U2af1 综合评分: 0.150 · 证据 1 条
• CSTF2T 综合评分: 0.100 · 证据 2 条
• EIF4A3 综合评分: 0.100 · 证据 2 条
• ELAVL3 综合评分: 0.100 · 证据 1 条
• NXF1 综合评分: 0.100 · 证据 1 条

该基因暂无关联疾病记录