🧬 基因注释：SNRPB
📝 官方信息
官方名称：small nuclear ribonucleoprotein polypeptides B and B1
功能摘要：The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- FUS 综合评分: 0.474 · 证据 1 条
- HNRNPH1 综合评分: 0.474 · 证据 2 条
- RBFOX2 综合评分: 0.474 · 证据 2 条
- fus 综合评分: 0.474 · 证据 1 条
- PTBP1 综合评分: 0.444 · 证据 2 条
- Tardbp 综合评分: 0.438 · 证据 1 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- HNRNPL 综合评分: 0.362 · 证据 2 条
- PCBP2 综合评分: 0.360 · 证据 1 条
- HNRNPC 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- QKI 综合评分: 0.350 · 证据 1 条
- EWSR1 综合评分: 0.348 · 证据 2 条
- TIA1 综合评分: 0.348 · 证据 1 条
- RBM15 综合评分: 0.312 · 证据 2 条
- HNRNPK 综合评分: 0.300 · 证据 2 条
- HNRNPU 综合评分: 0.300 · 证据 2 条
- KHSRP 综合评分: 0.300 · 证据 2 条
- SRSF2 综合评分: 0.300 · 证据 1 条
🏥 关联疾病
cerebrocostomandibular syndrome
高关联 (0.763)
Cerebro-costo-mandibular syndrome
高关联 (0.745)
neurodegenerative disease
中关联 (0.498)
cerebral cavernous malformation
低关联 (0.376)
dengue disease
低关联 (0.370)
cleft palate
低关联 (0.370)
Pierre-Robin sequence
低关联 (0.259)
Intellectual disability
低关联 (0.259)
isolated Pierre-Robin syndrome
低关联 (0.259)
genetic disorder
低关联 (0.188)