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🧬 基因注释:SNW1

📝 官方信息

官方名称:SNW domain containing 1

功能摘要:This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].

🎯 作为靶基因的剪接因子
  • FUS 综合评分: 0.424 · 证据 1 条
  • fus 综合评分: 0.424 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • HNRNPL 综合评分: 0.398 · 证据 2 条
  • PTBP1 综合评分: 0.398 · 证据 2 条
  • SRSF2 综合评分: 0.362 · 证据 1 条
  • Tardbp 综合评分: 0.356 · 证据 1 条
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • RBM10 综合评分: 0.312 · 证据 2 条
  • RBM39 综合评分: 0.312 · 证据 2 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • SRSF9 综合评分: 0.300 · 证据 1 条
  • Srsf2 综合评分: 0.300 · 证据 1 条
  • U2af2 综合评分: 0.286 · 证据 1 条
  • Rnps1 综合评分: 0.274 · 证据 1 条
  • Rbmx 综合评分: 0.260 · 证据 1 条
  • UPF1 综合评分: 0.260 · 证据 1 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
🏥 关联疾病
cancer
中关联 (0.579)
dengue disease
低关联 (0.370)
neurodegenerative disease
低关联 (0.261)
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🔗 外部数据库链接