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🧬 基因注释:SRSF7

📝 官方信息

官方名称:serine and arginine rich splicing factor 7

功能摘要:The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an N-terminal RNA recognition motif (RRM) for binding RNA and a C-terminal RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2018].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.536 · 证据 2 条
  • Srsf3 综合评分: 0.460 · 证据 1 条
  • FUS 综合评分: 0.444 · 证据 1 条
  • fus 综合评分: 0.444 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • HNRNPM 综合评分: 0.412 · 证据 2 条
  • Tardbp 综合评分: 0.408 · 证据 1 条
  • KHSRP 综合评分: 0.362 · 证据 2 条
  • SRSF9 综合评分: 0.362 · 证据 1 条
  • Srsf2 综合评分: 0.362 · 证据 1 条
  • HNRNPA1 综合评分: 0.350 · 证据 2 条
  • HNRNPH1 综合评分: 0.350 · 证据 2 条
  • EWSR1 综合评分: 0.348 · 证据 2 条
  • U2af2 综合评分: 0.322 · 证据 1 条
  • RBM15 综合评分: 0.312 · 证据 2 条
  • RBM39 综合评分: 0.312 · 证据 2 条
  • TIA1 综合评分: 0.312 · 证据 1 条
  • HNRNPD 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
🏥 关联疾病
neurodegenerative disease
中关联 (0.536)
dengue disease
低关联 (0.370)
cystitis
低关联 (0.262)
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🔗 外部数据库链接