🧬 基因注释：SSB
📝 官方信息
官方名称：small RNA binding exonuclease protection factor La
功能摘要：The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein. [provided by RefSeq, Jun 2014].
🎯 作为靶基因的剪接因子
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- HNRNPM 综合评分: 0.412 · 证据 2 条
- KHSRP 综合评分: 0.398 · 证据 2 条
- Srsf3 综合评分: 0.398 · 证据 1 条
- HNRNPL 综合评分: 0.362 · 证据 2 条
- RBFOX2 综合评分: 0.362 · 证据 2 条
- SRSF2 综合评分: 0.362 · 证据 1 条
- SRSF9 综合评分: 0.362 · 证据 1 条
- Srsf2 综合评分: 0.362 · 证据 1 条
- HNRNPC 综合评分: 0.350 · 证据 2 条
- RBM10 综合评分: 0.312 · 证据 2 条
- RBM39 综合评分: 0.312 · 证据 2 条
- FUS 综合评分: 0.300 · 证据 1 条
- PTBP1 综合评分: 0.300 · 证据 2 条
- SRSF3 综合评分: 0.300 · 证据 1 条
- fus 综合评分: 0.300 · 证据 1 条
- Ptbp2 综合评分: 0.298 · 证据 1 条
- PRPF8 综合评分: 0.262 · 证据 1 条
- EWSR1 综合评分: 0.250 · 证据 2 条
- FUBP1 综合评分: 0.250 · 证据 2 条
🏥 关联疾病
neurodegenerative disease
中关联 (0.544)
disease of peritoneum
低关联 (0.281)
Abnormality of the gastrointestinal tract
低关联 (0.281)
Alzheimer disease
低关联 (0.236)
Parkinson disease
低关联 (0.234)
lysosomal storage disease
低关联 (0.234)
multiple sclerosis
低关联 (0.234)
Hypercholesterolemia
低关联 (0.232)
genetic disorder
低关联 (0.118)