🧬 基因注释：TAF11

官方名称：TATA-box binding protein associated factor 11

功能摘要：Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012].

• HNRNPC 综合评分: 0.524 · 证据 2 条
• FUS 综合评分: 0.496 · 证据 1 条
• fus 综合评分: 0.496 · 证据 1 条
• HNRNPA2B1 综合评分: 0.412 · 证据 2 条
• U2af2 综合评分: 0.342 · 证据 1 条
• U2af1 综合评分: 0.324 · 证据 1 条
• KHSRP 综合评分: 0.300 · 证据 2 条
• RBFOX2 综合评分: 0.300 · 证据 2 条
• SRSF9 综合评分: 0.300 · 证据 1 条
• PCBP2 综合评分: 0.298 · 证据 1 条
• PRPF8 综合评分: 0.298 · 证据 1 条
• Rbmx 综合评分: 0.296 · 证据 1 条
• CELF2 综合评分: 0.274 · 证据 2 条
• EWSR1 综合评分: 0.250 · 证据 2 条
• RBM10 综合评分: 0.250 · 证据 2 条
• RBM15 综合评分: 0.250 · 证据 2 条
• TIA1 综合评分: 0.250 · 证据 1 条
• CSTF2 综合评分: 0.248 · 证据 2 条
• Tardbp 综合评分: 0.248 · 证据 1 条
• ELAVL3 综合评分: 0.224 · 证据 1 条

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