🧬 基因注释：THOC6
📝 官方信息
官方名称：THO complex subunit 6
功能摘要：This gene encodes a subunit of the multi-protein THO complex, which is involved in coordination between transcription and mRNA processing. The THO complex is a component of the TREX (transcription/export) complex, which is involved in transcription and export of mRNAs. A missense mutation in this gene is associated with a neurodevelopmental disorder called Beaulieu-Boycott-Innes syndrome. [provided by RefSeq, Dec 2016].
🎯 作为靶基因的剪接因子
- HNRNPC 综合评分: 0.448 · 证据 2 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- RBFOX2 综合评分: 0.398 · 证据 2 条
- HNRNPH1 综合评分: 0.350 · 证据 2 条
- FUS 综合评分: 0.300 · 证据 1 条
- fus 综合评分: 0.300 · 证据 1 条
- RBM10 综合评分: 0.250 · 证据 2 条
- RBM15 综合评分: 0.250 · 证据 2 条
- TIA1 综合评分: 0.250 · 证据 1 条
- GRSF1 综合评分: 0.248 · 证据 2 条
- U2af1 综合评分: 0.248 · 证据 1 条
- Rnps1 综合评分: 0.244 · 证据 1 条
- Rbmx 综合评分: 0.224 · 证据 1 条
- Srsf1 综合评分: 0.212 · 证据 1 条
- Srsf3 综合评分: 0.212 · 证据 1 条
- Tardbp 综合评分: 0.212 · 证据 1 条
- PCBP2 综合评分: 0.200 · 证据 1 条
- PRPF8 综合评分: 0.200 · 证据 1 条
- Rbm7 综合评分: 0.198 · 证据 1 条
- YBX1 综合评分: 0.198 · 证据 1 条
🏥 关联疾病
THOC6-related developmental delay-microcephaly-facial dysmorphism syndrome
高关联 (0.785)
genetic disorder
中关联 (0.517)
neurodegenerative disease
中关联 (0.461)
Intellectual disability
低关联 (0.383)
dystonia, early-onset, and/or spastic paraplegia
低关联 (0.161)