🧬 基因注释：TIMP1

官方名称：TIMP metallopeptidase inhibitor 1

功能摘要：This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008].

• HNRNPA2B1 综合评分: 0.412 · 证据 2 条
• Tardbp 综合评分: 0.398 · 证据 1 条
• HNRNPK 综合评分: 0.362 · 证据 2 条
• PTBP1 综合评分: 0.362 · 证据 2 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• RBM10 综合评分: 0.312 · 证据 2 条
• RBFOX2 综合评分: 0.300 · 证据 2 条
• SRSF3 综合评分: 0.300 · 证据 1 条
• SRSF9 综合评分: 0.300 · 证据 1 条
• PCBP1 综合评分: 0.262 · 证据 2 条
• PCBP2 综合评分: 0.262 · 证据 1 条
• UPF1 综合评分: 0.260 · 证据 1 条
• TFIP11 综合评分: 0.212 · 证据 1 条
• Mbnl2 综合评分: 0.200 · 证据 1 条
• PRPF8 综合评分: 0.200 · 证据 1 条
• Rnps1 综合评分: 0.198 · 证据 1 条
• Rbmx 综合评分: 0.162 · 证据 1 条
• U2af2 综合评分: 0.162 · 证据 1 条
• ACIN1 综合评分: 0.150 · 证据 2 条
• AQR 综合评分: 0.150 · 证据 1 条

该基因暂无关联疾病记录