🧬 基因注释：TK1
📝 官方信息
官方名称：thymidine kinase 1
功能摘要：The protein encoded by this gene is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. The encoded protein, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers. [provided by RefSeq, Oct 2016].
🎯 作为靶基因的剪接因子
- RBFOX2 综合评分: 0.529 · 证据 2 条
- HNRNPC 综合评分: 0.510 · 证据 2 条
- PTBP1 综合评分: 0.460 · 证据 2 条
- Srsf3 综合评分: 0.424 · 证据 1 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- HNRNPM 综合评分: 0.412 · 证据 2 条
- PCBP2 综合评分: 0.360 · 证据 1 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- Rnps1 综合评分: 0.336 · 证据 1 条
- Tardbp 综合评分: 0.336 · 证据 1 条
- RBM15 综合评分: 0.312 · 证据 2 条
- FUS 综合评分: 0.300 · 证据 1 条
- HNRNPK 综合评分: 0.300 · 证据 2 条
- SRSF3 综合评分: 0.300 · 证据 1 条
- fus 综合评分: 0.300 · 证据 1 条
- GRSF1 综合评分: 0.274 · 证据 2 条
- SF3A3 综合评分: 0.262 · 证据 1 条
- YBX1 综合评分: 0.260 · 证据 1 条
- EWSR1 综合评分: 0.250 · 证据 2 条
- RBM10 综合评分: 0.250 · 证据 2 条
🏥 关联疾病
该基因暂无关联疾病记录