🧬 基因注释：TM2D1

官方名称：TM2 domain containing 1

功能摘要：The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for this gene. [provided by RefSeq, Feb 2016].

• HNRNPC 综合评分: 0.564 · 证据 2 条
• HNRNPL 综合评分: 0.398 · 证据 2 条
• FUS 综合评分: 0.362 · 证据 1 条
• KHSRP 综合评分: 0.362 · 证据 2 条
• PTBP1 综合评分: 0.362 · 证据 2 条
• fus 综合评分: 0.362 · 证据 1 条
• HNRNPA1 综合评分: 0.350 · 证据 2 条
• HNRNPA2B1 综合评分: 0.350 · 证据 2 条
• ELAVL3 综合评分: 0.322 · 证据 1 条
• EWSR1 综合评分: 0.312 · 证据 2 条
• FUBP1 综合评分: 0.312 · 证据 2 条
• HNRNPD 综合评分: 0.300 · 证据 2 条
• HNRNPU 综合评分: 0.300 · 证据 2 条
• RBFOX2 综合评分: 0.300 · 证据 2 条
• SRSF9 综合评分: 0.300 · 证据 1 条
• U2af2 综合评分: 0.286 · 证据 1 条
• RBM10 综合评分: 0.250 · 证据 2 条
• TIA1 综合评分: 0.250 · 证据 1 条
• Tardbp 综合评分: 0.248 · 证据 1 条
• Rnps1 综合评分: 0.224 · 证据 1 条

该基因暂无关联疾病记录