🧬 基因注释：TNFRSF10C
📝 官方信息
官方名称：TNF receptor superfamily member 10c
功能摘要：The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- PRPF8 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录