🧬 基因注释:TREM1
📝 官方信息
官方名称:triggering receptor expressed on myeloid cells 1
功能摘要:This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011].
🎯 作为靶基因的剪接因子
- EWSR1 置信度: 2.0
🏥 关联疾病
该基因暂无关联疾病记录