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🧬 基因注释:TRIM23

📝 官方信息

官方名称:tripartite motif containing 23

功能摘要:The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.412 · 证据 2 条
  • Tardbp 综合评分: 0.372 · 证据 1 条
  • FUS 综合评分: 0.362 · 证据 1 条
  • fus 综合评分: 0.362 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.350 · 证据 2 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • MBNL2 综合评分: 0.298 · 证据 1 条
  • Ptbp2 综合评分: 0.262 · 证据 1 条
  • U2af2 综合评分: 0.260 · 证据 1 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • FUBP1 综合评分: 0.250 · 证据 2 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • CPSF6 综合评分: 0.212 · 证据 2 条
  • Mbnl2 综合评分: 0.200 · 证据 1 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
  • EIF4A3 综合评分: 0.162 · 证据 2 条
  • ELAVL3 综合评分: 0.162 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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