🧬 基因注释：TSC22D1
📝 官方信息
官方名称：TSC22 domain family member 1
功能摘要：This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011].
🎯 作为靶基因的剪接因子
- FUS 综合评分: 0.486 · 证据 1 条
- fus 综合评分: 0.486 · 证据 1 条
- HNRNPC 综合评分: 0.448 · 证据 2 条
- MBNL2 综合评分: 0.442 · 证据 1 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- RBFOX2 综合评分: 0.398 · 证据 2 条
- HNRNPU 综合评分: 0.362 · 证据 2 条
- Srsf3 综合评分: 0.362 · 证据 1 条
- Tardbp 综合评分: 0.356 · 证据 1 条
- HNRNPH1 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- QKI 综合评分: 0.350 · 证据 1 条
- U2af2 综合评分: 0.314 · 证据 1 条
- HNRNPD 综合评分: 0.300 · 证据 2 条
- HNRNPK 综合评分: 0.300 · 证据 2 条
- HNRNPL 综合评分: 0.300 · 证据 2 条
- KHSRP 综合评分: 0.300 · 证据 2 条
- PTBP1 综合评分: 0.300 · 证据 2 条
- SRSF2 综合评分: 0.300 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录