🧬 基因注释：TFE3

官方名称：transcription factor binding to IGHM enhancer 3

功能摘要：This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013].

• HNRNPA2B1 综合评分: 0.448 · 证据 2 条
• HNRNPC 综合评分: 0.448 · 证据 2 条
• HNRNPH1 综合评分: 0.350 · 证据 2 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• PCBP2 综合评分: 0.344 · 证据 1 条
• RBM10 综合评分: 0.312 · 证据 2 条
• HNRNPK 综合评分: 0.300 · 证据 2 条
• HNRNPU 综合评分: 0.300 · 证据 2 条
• PTBP1 综合评分: 0.300 · 证据 2 条
• RBFOX2 综合评分: 0.300 · 证据 2 条
• SRSF3 综合评分: 0.300 · 证据 1 条
• Srsf3 综合评分: 0.300 · 证据 1 条
• U2af2 综合评分: 0.286 · 证据 1 条
• ELAVL3 综合评分: 0.260 · 证据 1 条
• RBM15 综合评分: 0.250 · 证据 2 条
• UPF1 综合评分: 0.244 · 证据 1 条
• Rbmx 综合评分: 0.224 · 证据 1 条
• YBX1 综合评分: 0.224 · 证据 1 条
• AQR 综合评分: 0.212 · 证据 1 条
• PRPF4 综合评分: 0.212 · 证据 1 条

该基因暂无关联疾病记录