SpliceAtlasDB
← 返回基因注释查询

🧬 基因注释:TMEFF2

📝 官方信息

官方名称:transmembrane protein with EGF like and two follistatin like domains 2

功能摘要:This gene encodes a member of the tomoregulin family of transmembrane proteins. This protein has been shown to function as both an oncogene and a tumor suppressor depending on the cellular context and may regulate prostate cancer cell invasion. Multiple soluble forms of this protein have been identified that arise from both an alternative splice variant and ectodomain shedding. Additionally, this gene has been found to be hypermethylated in multiple cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015].

🎯 作为靶基因的剪接因子
  • FUS 综合评分: 0.300 · 证据 1 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • fus 综合评分: 0.300 · 证据 1 条
  • Ptbp2 综合评分: 0.262 · 证据 1 条
  • Mbnl2 综合评分: 0.200 · 证据 1 条
  • Nova2 综合评分: 0.200 · 证据 1 条
  • ELAVL3 综合评分: 0.198 · 证据 1 条
  • Srsf3 综合评分: 0.150 · 证据 1 条
  • Tardbp 综合评分: 0.150 · 证据 1 条
  • U2af1 综合评分: 0.150 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

🔗 外部数据库链接