🧬 基因注释:TRRAP
📝 官方信息
官方名称:transformation/transcription domain associated protein
功能摘要:This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].
🎯 作为靶基因的剪接因子
- HNRNPA2B1 综合评分: 0.564 · 证据 2 条
- Tardbp 综合评分: 0.550 · 证据 1 条
- FUS 综合评分: 0.496 · 证据 1 条
- fus 综合评分: 0.496 · 证据 1 条
- PTBP1 综合评分: 0.460 · 证据 2 条
- HNRNPL 综合评分: 0.424 · 证据 2 条
- Srsf3 综合评分: 0.424 · 证据 1 条
- HNRNPC 综合评分: 0.412 · 证据 2 条
- CELF2 综合评分: 0.372 · 证据 2 条
- HNRNPD 综合评分: 0.362 · 证据 2 条
- RBFOX2 综合评分: 0.362 · 证据 2 条
- HNRNPA1 综合评分: 0.350 · 证据 2 条
- HNRNPH1 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- EWSR1 综合评分: 0.348 · 证据 2 条
- MBNL2 综合评分: 0.344 · 证据 1 条
- Ptbp2 综合评分: 0.324 · 证据 1 条
- RBM10 综合评分: 0.312 · 证据 2 条
- ACIN1 综合评分: 0.310 · 证据 2 条
🏥 关联疾病
该基因暂无关联疾病记录