🧬 基因注释：UBE2C

官方名称：ubiquitin conjugating enzyme E2 C

功能摘要：The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19. [provided by RefSeq, Aug 2013].

• HNRNPC 综合评分: 0.510 · 证据 2 条
• HNRNPA2B1 综合评分: 0.474 · 证据 2 条
• HNRNPH1 综合评分: 0.412 · 证据 2 条
• RBFOX2 综合评分: 0.362 · 证据 2 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• FUBP1 综合评分: 0.312 · 证据 2 条
• RBM15 综合评分: 0.312 · 证据 2 条
• FUS 综合评分: 0.300 · 证据 1 条
• HNRNPK 综合评分: 0.300 · 证据 2 条
• KHSRP 综合评分: 0.300 · 证据 2 条
• PTBP1 综合评分: 0.300 · 证据 2 条
• SRSF9 综合评分: 0.300 · 证据 1 条
• fus 综合评分: 0.300 · 证据 1 条
• PCBP2 综合评分: 0.298 · 证据 1 条
• Srsf3 综合评分: 0.294 · 证据 1 条
• Rbmx 综合评分: 0.286 · 证据 1 条
• Srsf1 综合评分: 0.274 · 证据 1 条
• PRPF8 综合评分: 0.262 · 证据 1 条
• RBM10 综合评分: 0.250 · 证据 2 条
• TIA1 综合评分: 0.250 · 证据 1 条

该基因暂无关联疾病记录