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🧬 基因注释:USP10

📝 官方信息

官方名称:ubiquitin specific peptidase 10

功能摘要:Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2013].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.448 · 证据 2 条
  • HNRNPM 综合评分: 0.448 · 证据 2 条
  • HNRNPU 综合评分: 0.424 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • RBFOX2 综合评分: 0.398 · 证据 2 条
  • HNRNPK 综合评分: 0.362 · 证据 2 条
  • PTBP1 综合评分: 0.362 · 证据 2 条
  • HNRNPA1 综合评分: 0.350 · 证据 2 条
  • HNRNPH1 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • QKI 综合评分: 0.350 · 证据 1 条
  • Tardbp 综合评分: 0.336 · 证据 1 条
  • RBM22 综合评分: 0.312 · 证据 2 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • HNRNPD 综合评分: 0.300 · 证据 2 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • SRSF2 综合评分: 0.300 · 证据 1 条
  • SRSF9 综合评分: 0.300 · 证据 1 条
  • Srsf2 综合评分: 0.300 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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