🧬 基因注释：VPREB3
📝 官方信息
官方名称：V-set pre-B cell surrogate light chain 3
功能摘要：The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR). While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas. [provided by RefSeq, Apr 2015].
🎯 作为靶基因的剪接因子
- Rbmx 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录