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🧬 基因注释:VPS4B

📝 官方信息

官方名称:vacuolar protein sorting 4 homolog B

功能摘要:The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • FUS 综合评分: 0.424 · 证据 1 条
  • fus 综合评分: 0.424 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • Tardbp 综合评分: 0.364 · 证据 1 条
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • RBM10 综合评分: 0.312 · 证据 2 条
  • TIA1 综合评分: 0.312 · 证据 1 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • MBNL2 综合评分: 0.298 · 证据 1 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • FUBP1 综合评分: 0.250 · 证据 2 条
  • RBM39 综合评分: 0.250 · 证据 2 条
  • CPSF6 综合评分: 0.212 · 证据 2 条
  • U2af1 综合评分: 0.212 · 证据 1 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
  • ELAVL3 综合评分: 0.198 · 证据 1 条
  • Rbmx 综合评分: 0.162 · 证据 1 条
  • Rbpms 综合评分: 0.162 · 证据 1 条
  • Rnps1 综合评分: 0.162 · 证据 1 条
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