🧬 基因注释：WFDC8
📝 官方信息
官方名称：WAP four-disulfide core domain 8
功能摘要：This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains a Kunitz-inhibitor domain, in addition to three WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Two alternatively spliced transcript variants have been found for this gene, and they encode the same protein. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- U2af1 综合评分: 0.310 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录