SpliceAtlasDB
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🧬 基因注释:YARS1

📝 官方信息

官方名称:tyrosyl-tRNA synthetase 1

功能摘要:Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.448 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • PTBP1 综合评分: 0.398 · 证据 2 条
  • HNRNPU 综合评分: 0.362 · 证据 2 条
  • SRSF2 综合评分: 0.362 · 证据 1 条
  • SRSF9 综合评分: 0.362 · 证据 1 条
  • HNRNPA1 综合评分: 0.350 · 证据 2 条
  • HNRNPH1 综合评分: 0.350 · 证据 2 条
  • HNRNPM 综合评分: 0.350 · 证据 2 条
  • Tardbp 综合评分: 0.346 · 证据 1 条
  • PRPF8 综合评分: 0.324 · 证据 1 条
  • UPF1 综合评分: 0.314 · 证据 1 条
  • RBM10 综合评分: 0.312 · 证据 2 条
  • RBM15 综合评分: 0.312 · 证据 2 条
  • RBM22 综合评分: 0.312 · 证据 2 条
  • TIA1 综合评分: 0.312 · 证据 1 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • HNRNPK 综合评分: 0.300 · 证据 2 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
🏥 关联疾病

该基因暂无关联疾病记录

🔗 外部数据库链接