🧬 基因注释：YWHAZ
📝 官方信息
官方名称：tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
功能摘要：This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008].
🎯 作为靶基因的剪接因子
- PTBP1 综合评分: 0.529 · 证据 2 条
- RBFOX2 综合评分: 0.486 · 证据 2 条
- Nova2 综合评分: 0.484 · 证据 1 条
- Srsf3 综合评分: 0.460 · 证据 1 条
- QKI 综合评分: 0.448 · 证据 1 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- HNRNPC 综合评分: 0.412 · 证据 2 条
- HNRNPL 综合评分: 0.362 · 证据 2 条
- SRSF2 综合评分: 0.362 · 证据 1 条
- Mbnl2 综合评分: 0.360 · 证据 1 条
- PCBP2 综合评分: 0.360 · 证据 1 条
- HNRNPA1 综合评分: 0.350 · 证据 2 条
- HNRNPH1 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- TIA1 综合评分: 0.348 · 证据 1 条
- CELF2 综合评分: 0.324 · 证据 2 条
- EWSR1 综合评分: 0.312 · 证据 2 条
- RBM22 综合评分: 0.312 · 证据 2 条
- UPF1 综合评分: 0.306 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录