🧬 基因注释：YWHAE
官方名称：tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
功能摘要：This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008].
- FUS 综合评分: 0.522 · 证据 1 条
- fus 综合评分: 0.522 · 证据 1 条
- HNRNPC 综合评分: 0.510 · 证据 2 条
- Tardbp 综合评分: 0.501 · 证据 1 条
- PTBP1 综合评分: 0.496 · 证据 2 条
- RBFOX2 综合评分: 0.496 · 证据 2 条
- HNRNPK 综合评分: 0.424 · 证据 2 条
- Srsf3 综合评分: 0.424 · 证据 1 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- KHSRP 综合评分: 0.398 · 证据 2 条
- EWSR1 综合评分: 0.374 · 证据 2 条
- ELAVL3 综合评分: 0.372 · 证据 1 条
- SRSF2 综合评分: 0.362 · 证据 1 条
- SRSF9 综合评分: 0.362 · 证据 1 条
- Srsf2 综合评分: 0.362 · 证据 1 条
- Nova2 综合评分: 0.360 · 证据 1 条
- HNRNPH1 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- PCBP2 综合评分: 0.344 · 证据 1 条
该基因暂无关联疾病记录