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基因注释:ZNF879

官方信息

官方名称:zinc finger protein 879

功能摘要:This gene encodes a kruppel-associated box-containing zinc finger protein (KRAB-ZFP). The encoded protein contains an N-terminal kruppel-associated box (KRAB) domain and thirteen C-terminal C2H2-type zinc finger domains. The KRAB-ZFPs represent the largest family of mammalian transcriptional repressors, which function through the recruitment of the nuclear co-factor KRAB-Associated Protein 1 (KAP1), to engage histone modifiers and induce heterochromatin formation. [provided by RefSeq, Jul 2017].

作为靶基因的剪接因子
  • HNRNPA2B1 综合评分: 0.350 · 证据 2 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
  • U2af1 综合评分: 0.150 · 证据 1 条
  • Rbmx 综合评分: 0.100 · 证据 1 条
关联疾病

该基因暂无关联疾病记录

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